Vol. 6 No. 01 (2025)
Articles

Evaluating the Effects of Energy Drink Consumption on Liver Function among Students and Staff at Cihan University, Duhok, Iraq

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  • Kajeen Hassan Jasim,
  • Barhav Issa Abdullah,
  • Khalida Mohamed Hasan,
  • Layla Mohamed Salih,
  • Jihan Hasan Jasim
Kajeen Hassan Jasim
Department of Medical Laboratory, College of Health Science, Cihan University-Duhok, Iraq
Barhav Issa Abdullah
Department of Medical Laboratory, College of Health Science, University of Duhok, Duhok, Iraq
Khalida Mohamed Hasan
Department of Medical Laboratory, College of Health Science, Cihan University-Duhok, Iraq
Layla Mohamed Salih
Department of Medical Laboratory, College of Health Science, Cihan University-Duhok, Iraq
Jihan Hasan Jasim
Department of Medical Laboratory, College of Health Science, University of Duhok, Duhok, Iraq
DOI: https://doi.org/10.38094/jlbsr601151

Published 2025-06-23

Keywords

  • ALT,
  • AST,
  • Energy drink,
  • liver disease,
  • vitamin B12

How to Cite

Jasim, K., Abdullah, B., Hasan, K., Salih, L., & Jasim , J. (2025). Evaluating the Effects of Energy Drink Consumption on Liver Function among Students and Staff at Cihan University, Duhok, Iraq. Journal of Life and Bio Sciences Research , 6(01), 50 - 54. https://doi.org/10.38094/jlbsr601151

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Abstract

Energy drinks (ED) have been related to many health issues, including elevated pressure, cardiovascular difficulties, head pain, rest disruptions, drug overuse, tension and excitement. The purpose of the current research is the estimate of the association between individuals with energy drinks and without them and to estimate the impact of energy drinks on liver metabolic. The current cross-sectional study included 50 individuals, aged 18 to 40, who were divided into two groups: (1) a healthy group (n=25) consisting of individuals who did not consume energy drinks, and (2) a case group (n=25) comprising individuals who regularly consumed energy drinks. Aspartate aminotransferase (AST) and alanine transaminase (ALT) liver enzymes were estimated by using spectrophotometry, while vitamin B12 levels were assessed using the VIDAS® apparatus. Anthropometric measurements were also recorded for all participants. The findings revealed a significant elevation in AST, ALT value and vitamin B12 in the drinkers of energy group in contrast to the healthy subjects (p<0.001). Additionally, males showed more pronounced increases in these markers than females p levels were lower than 0.001. In conclusion, the investigation discovered that energy drink consumption significantly elevates hepatocyte function markers (ALT and AST) and anthropometric parameters. It also highlighted that extreme energy drink intake may contribute to cases of severe liver damage.

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References

  1. Al-Habib, O.A., AL-Kass, S.Y., Jasim, K.H. (2016). impact of nuts consumption on antioxidant status and pro-oxidant parameters in healthy human volunteers. Science Journal of University of Zakho, 4(1), 9-17.
  2. Al-Habib, O.A., Jasim, K.H. (2014). Impact of nuts consumption on blood pressure, glycemic status, lipid profile and total protein in healthy human volunteers. Science Journal of University of Zakho, 2(2), 228-238.
  3. Alsunni, A.A. (2015). Energy drink consumption: Beneficial and adverse health effects. International Journal of Health Sciences, 9(4), 468-476.
  4. Babu, K.M., Church, R.J., Gohil, K. (2018). The role of vitamin B12 and its excess in the metabolic pathway: Implications for energy drink consumption. Journal of Clinical Nutrition, 10(4), 567-573.
  5. Cabrera, C.A., Martinez, J.R., Rodriguez, L.P., Smith, B.D. (2016). The effects of energy drink consumption on kidney and liver function. Journal of Toxicology and Environmental Health, 79(2), 120-133.
  6. DiNicolantonio, J.J., O'Keefe, J.H., Lucan, S.C. (2018). The harmful effects of energy drinks on cardiovascular health: A review. International Journal of Cardiology, 262, 54-58.
  7. Ferdinand, K.C., Roberts, A.L., Thompson, J.P., and Wilson, M.G. (2019). Cardiovascular responses to energy drinks in a healthy population: The caffeine and taurine question. Journal of the American College of Cardiology, 73(12), 15-23.
  8. Goldfarb, M., Johnson, R. T., Williams, D. C., and Harris, P. K. (2014). The impact of energy drinks on metabolic processes. Journal of Clinical Nutrition and Metabolism, 58(3), 77-89.
  9. Gunja, N., Brown, J.A. (2012). Energy drinks: Health risks and toxicity. Medical Journal of Australia, 196(1), 46-49.
  10. Higgins, J. P., Babu, K., Deuster, P. A., Shearer, J. (2015). Risk assessment of energy drinks with focus on cardiovascular effects. Food and Chemical Toxicology, 80(5), 46-56.
  11. Higgins, J.P., Ortiz, B.L., Littrell, K.H., Babu, K. (2018). Energy drinks and cardiovascular complications: A review. Trends in Cardiovascular Medicine, 28(3), 234-242.
  12. Kanter, M., Reynolds, M.P., Chen, X., Thomas, S.H. (2012). The dark side of energy drinks: A comprehensive review of their impact on the human body. Nutrition Reviews, 70(12), 689-701.
  13. Keller, S. T., Haskins, J., Williams, S. (2020). Impact of caffeine and taurine in energy drinks on liver function. Journal of Clinical Pharmacology, 60(3), 346-351.
  14. Krentz, A. J., Kahn, S.E., Peters, A.L., Hirsch, I.B. (2013). The metabolic effects of energy drink ingredients. British Journal of Clinical Pharmacology, 76(4), 577-592.
  15. Markon, A.O., Ding, M., Chavarro, J.E., Wolpert, B.J. (2023). Demographic and behavioural correlates of energy drink consumption. Public health nutrition, 26(7), 1424-1435.
  16. McCusker, R.R., Goldberger, B.A., Cone, E.J. (2015). The effects of energy drink ingredients on health: A review of the literature. Clinical Toxicology, 53(7), 646-654.
  17. Nawrot, P., Jordan, S., Jansen, S. (2022). Cardiovascular and metabolic effects of energy drinks: A systematic review. European Journal of Nutrition, 61(1), 1-9.
  18. Nowak, D., Jasionowski, A., Ratajczak, P., Waskiewicz, Z. (2018). How do energy drinks affect the liver and kidney function? Clinical Toxicology Reports, 56(3), 191-205.
  19. Palliser, H.K., Spector, R., Smith, D. (2020). Energy drinks: Composition and metabolic effects. Nutrition and Metabolism, 17(1), 16.
  20. Piccioni, A., Covino, M., Zanza, C., Longhitano, Y., Tullo, G., Bonadia, N., Franceschi, F. (2021). Energy drinks: a narrative review of their physiological and pathological effects. Internal Medicine Journal, 51(5), 636-646.
  21. Reddy, P., Subramanian, K., Sharma, G., Gupta, M. (2018). Liver function alterations due to excessive energy drink consumption. Hepatology Journal, 15(2), 99-112.
  22. Seifert, S.M., Schaechter, J.L., Hershorin, E.R., Lipshultz, S.E. (2011). Health effects of energy drinks on children, adolescents, and young adults. Pediatrics, 127(3), 511-528.
  23. Temple, J.L., Bernard, C., Lipton, R.B., Mahoney, C.R. (2017). Caffeine and the cardiovascular system: Implications of energy drink consumption. Current Cardiology Reports, 19(3), 21-35.
  24. Theodorakopoulou, M., Ortiz, A., Fernandez-Fernandez, B., Kanbay, M., Minutolo, R., Sarafidis, P.A., (2024). Guidelines for the management of hypertension in CKD patients: where do we stand in 2024? Clinical Kidney Journal, 17 (Supplement_2), 36-50.
  25. Tobias, D.K., Chen, M., Manson, J.E., Hu, F.B. (2019). Acute liver injury and energy drinks: Case reports and metabolic insights. Journal of Hepatology, 70(2), 334-341.
  26. Zha, L., Zhang, J., Wang, L. (2021). Excessive intake of vitamins and its consequences in energy drinks. Food and Chemical Toxicology, 150, 112073
  27. Zucconi, S., Volpato, C., Adinolfi, F., Gandini, E. (2013). The role of caffeine and taurine in energy drink-induced metabolic dysfunction. European Journal of Clinical Nutrition, 67(1), 76-83.

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